In an early-stage clinical trial, scientists used designer immune cells to “reboot” the immune systems of patients with various autoimmune diseases.
The trial used a form of chimeric antigen receptor (CAR) T cell therapy, which has become a mainstay treatment for blood cancers, like leukemia.
Only a few patients were included in this initial trial, and the trial was short — so it’s too early to say whether this treatment works over the long term. But markers of disease in the patients’ blood suggest the autoimmune processes had been shut down, at least for now.
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