By blocking the action of a single protein, scientists have extended the average life span of the mice in their experiment by around 25%. This recent finding has raised the question of whether such a treatment could ever work for people, and so far, there are some promising early hints that it might. In the … Read more
A single, small molecule can restore muscle strength, fuel brain cell growth and reduce inflammation in old mice, new research shows. So far, the anti-aging molecule has only been tested in rodents and in human cells in lab dishes. But the researchers say the results are compelling enough to move the compound toward human trials, … Read more
Proteins found in tiny, indestructible tardigrades could potentially be a key ingredient in slowing the aging process in humans, scientists claim. However, it will take more work to show these proteins are a veritable fountain of youth — for now, the researchers have only early hints from lab-dish experiments.. Also known as water bears, tardigrades … Read more
Scientists reversed some signs of immune aging in mice with a new treatment that could one day potentially be used in humans. The new immunotherapy works by disrupting a natural process by which the immune system becomes biased towards making one type of cell as it ages. The mouse study is an “important” proof-of-concept, but … Read more
Why do common shrews live for only two years, while bowhead whales survive for two centuries? And could the answer give us hints as to how to extend our own, human life spans? The maximum life span of each species is estimated using the age of its longest-living member, and these vary by orders of … Read more
Our “biological age,” which reflects signs of age-related decline in our cells and tissues, doesn’t steadily increase along with our chronological age. Instead, new research suggests that biological aging can accelerate during stressful events and then reverse after those events. In other words, there are measurable biological markers linked to age-related changes in cell function, … Read more
Scientists have long debated the greatest possible age of a person, with previous studies placing the limit at up to 150 years. But in the past 25 years, no one has surpassed the record for the world’s oldest person, held by Jean Louise Calment, who died at age 122 in 1997. “This has led people … Read more
Telomeres are the “caps” that protect the ends of DNA strands from being destroyed by a cell. They are made up of areas of repeated DNA sequences combined with specific proteins at the ends of chromosomes — the tightly wound structures of DNA and proteins inside cells. Telomeres play a role in how fast cells … Read more
Einstein’s theory of general relativity upended humanity’s understanding of the universe more than a century ago, and since then, scientists have discovered that the steady march of time is anything but steady. Among the haunting implications of general relativity is that time passes more quickly at the top of every staircase in the world than … Read more
In Boston labs, old, blind mice have regained their eyesight, developed smarter, younger brains and built healthier muscle and kidney tissue. On the flip side, young mice have prematurely aged, with devastating results to nearly every tissue in their bodies. The experiments show aging is a reversible process, capable of being driven “forwards and backwards … Read more
